At the IGTP TODAY

News

- Research

Air Pollution is Linked to Lower COVID-19 Vaccine Responses

People exposed to higher levels of air pollution before the pandemic had lower antibody responses to COVID-19 vaccines, according to a study led by the Barcelona Institute for Global Health (ISGlobal), an institution supported by "la Caixa" Foundation, in collaboration with the  Germans Trias i Pujol Research Institute (IGTP). In particular, exposure to fine particulate matter (PM2.5), nitrogen dioxide (NO2) and black carbon (BC) was associated with about a 10% decrease in IgM and IgG antibody responses in people without prior infection. The findings, published in Environmental Health Perspectives, provide further evidence on the adverse effects of air pollution on the immune system.

- Innovation, Research

Aniling, IGTP and ICO awarded €1.8 million from the Spanish government to develop a theragnostic tool for personalised management of colorectal cancer

The consortium made up of Aniling, the Germans Trias i Pujol Research Institute (IGTP) and the Institut Català d’Oncologia (ICO) has been awarded €1.8 million from the Spanish State Research Agency (AEI) for the development of a new theragnostic tool to personalise the management of colorectal cancer (CRC) patients.

- Research, Success Stories

The Clinical and Environmental Infectious Diseases Research Group signs a collaboration for the development of a new biocide for the treatment of drinking water

The Clinical and Environmental Infectious Diseases Research Group (CEID) has discovered a molecule of natural origin with a high bactericidal, amoebicidal and biofilm reduction capacity. The collaboration signed by the group's researchers with a private company will finance the improvement of the molecule's characteristics to be applied in large water installations, preventing water for human consumption from acting as a vehicle for the transmission of bacterial diseases.

- Research

Breaking barriers in hepatitis C diagnosis and treatment for populations at risk

A study with people who inject drugs evaluated a minimally invasive test based on dried blood spots (DBS) for the monitoring of hepatitis C virus (HCV) infection. The use of DBS samples for HCV RNA detection and genotyping was shown to effectively assess cure after treatment and to differentiate between reinfection and treatment failure. The results support the viability of decentralizing treatment and post-treatment monitoring for people who inject drugs, who frequently face challenges accessing the healthcare system. The study has been published in the Journal of Medical Virology.

- Research

New method for detecting nanoplastics in blood

A study uses for the first time flow cytometry to detect and measure nanoplastics in peripheral human blood. People with various medical conditions have been included in the study so as to investigate potential differences for nanoplastic accumulation across the population. In addition, mice have been used in a highly controlled environment to compare their nanoplastic levels to that of humans. This study, which has been published at the journal MethodsX.

- Institutional, Research

Women’s Day: giving our women scientists a voice

To commemorate International Women's Day, we asked four questions to different profiles of IGTP researchers to find out about the difficulties they have encountered as women scientists and how they see the future: Dr Carolina Armengol, leader of the consolidated Childhood Liver Oncology Research Group (c-LOG), Dr Raquel Guillamat, junior leader of the emerging group Translational Research in Pulmonary Immunity, and PhD student Daina Martínez from the ICREC laboratory of Cardiology Research.

- Research

Innovative technique to improve characterisation of ventricular tachycardia substrate

A study published in JACC: Clinical electrophysiology evaluates local impedance-based mapping as a tool to identify critical components of ventricular tachycardia after myocardial infarction. It highlights its potential to improve the characterisation of ventricular tachycardia tissues and circuits. The scientists conclude that the technique is feasible and could improve the results of cardiac ablation. The work, which was performed in an animal model, involved researchers from the Heart Failure and Heart Regeneration Research Group (ICREC) at the Germans Trias i Pujol Research Institute (IGTP), the Heart Institute of the Germans Trias Hospital (iCor), the Autonomous University of Barcelona (UAB) and Boston Scientific.

- Projects, Research

Funding of €1.2M from the Spanish Association Against Cancer for a research project on childhood liver cancer coordinated by IGTP

Encouraging news in the framework of the International Day Against Childhood Cancer. The Spanish Association Against Cancer, through its Aid Programmes, has granted 1.2 million euros to the coordinated project "Personalised Medicine for Childhood Liver Cancer". The five-year project will be coordinated by the Germans Trias i Pujol Research Institute (IGTP), under the leadership of Dr Carolina Armengol, with the participation of another four Spanish research groups. All participating groups are members of the CIBER of Hepatic and Digestive Diseases (CIBEREHD).