05/08/2022 - Research

GCAT contributes to identify a new genetic region linked with the severity of COVID-19 and to extensively characterize a chromosomal inversion

The Severe Covid-19 GWAS Group, the group that reported the first genetic analysis in early pandemic (NEJM, 2020), presents now the new results of an extended GWAS meta-analysis of a well-characterized cohort of 3,260 COVID-19 patients with respiratory failure and 12,483 population controls from Italy, Spain, Norway and Germany/Austria, that have been published in Human Molecular Genetics.

04/08/2022 - Research

Study identifies 11 new genetic regions linked with the susceptibility and severity of COVID-19

An international macro-study in which researchers from the GCAT|Genomes for Life project of the Germans Trias i Pujol Research Institute (IGTP) have participated has located 11 new chromosomal regions involved in susceptibility to SARS-CoV-2 infection and in severity COVID-19 clinic. The work is published in the journal Nature.

28/07/2022 - Research

A community-based intervention for the micro-elimination of hepatitis C in the Pakistani population in Catalonia

Since 2019, around 1,000 immigrants from endemic countries have participated in a new model of diagnosis and management of viral hepatitis that has been designed by the Clinical Virology and New Diagnostic Approaches Research Group of the Germans Trias i Pujol Research Institute (IGTP), in the Microbiology Service of the Germans Trial Hospital (headed by Dr. Elisa Martró), along with the Public and Community Health Team (eSPiC) of Drassanes-Vall d'Hebron International Health Unit.

01/07/2022 - Research

The IGTP coordinating two out of nine COST Actions coming to Spain and participating in a third

The COST Programme (European Cooperation in Science and Technology) has approved 70 new actions and Spain is coordinating nine of them, making it second in the ranking of countries leading COST Actions after Italy, which is coordinating ten. Three of the Spanish projects are from the Germans Trias i Pujol Research Institute (IGTP) and two of these are being led by the IGTP. COST Actions run for four years and this round will start in the coming autumn.

07/06/2022 - Research

The IGTP and the Clinical Laboratory North Metropolitan Area are the first to publish the complete sequence of a sample of monkey pox virus

The IGTP and the Microbiology Service of the Clinical Laboratory of the North Metropolitan Area led by the researcher Elisa Martró have been the first to carry out the complete sequencing of a sample of monkey pox virus in Spain. This is a milestone in itself, but will also be fundamental for epidemiological surveillance of the infection and the study of future outbreaks as it provides a description of the genetic material of the virus.

21/03/2022 - Research

No increased risk of diabetes type 1 for children of women treated with betamethasone during pregnancy

The Immunology of Diabetes group have published a study evaluating the effect of prenatal exposure to betamethasone on the risk of developing diabetes type 1 in the Journal of Diabetes Research.

17/03/2022 - Research

Researchers from Germans Trias and Mateu Orfila Hospital in Menorca identify a new subtype of ataxia

The article describing the new SCA49 subtype has been published in the journal Brain Communications, and is featured as a highlight by its Editorial Board. The new ataxia subtype has been identified by studying members of one family from the island of Menorca. The finding provides a better understanding of the pathological basis of ataxia and opens the door to pre-symptomatic diagnoses and genetic counselling for people with the disorder.

03/03/2022 - Research

New biomarkers to monitor and predict the remission phase (honeymoon) in children with type 1 diabetes

A study led by researchers from the Germans Trias i Pujol Research Institute (IGTP) and the Parc Tauli Hospital published in Frontiers in Immunology shows that a sample of peripheral blood can be used to identify levels of cells and molecules of the immune system that are specifically altered during the remission phase in paediatric type 1 diabetes (T1D). These can be used to monitor this phase and predict the progress of the disease.

18/02/2022 - Research

The generation of human neurofibromas in mice opens the door to testing new treatments

The Hereditary Cancer Group have published a study in Cell Reports in which they describe the generation of a model system based on induced pluripotent stem cells (iPSCs) that is able to generate human neurofibromas in mice. These tumours arise in people with the genetic disease Neurofibromatosis Type 1, a prevalent condition occurring in one in every 3,000 people. To date, a robust method for generating human neurofibromas in mice has been lacking, and the model developed opens up the possibility of testing new treatments for these tumours.

15/02/2022 - Research

The RIGHT PLUS Network presents the results of the LAMIS study on sexual health in gay men and MSN in Latin America

The RIGHT PLUS Network has presented the executive summary of the Latin American MSM (men who have sex with men) Internet Survey (LAMIS-20218), in which 64,655 men who have sex with men in Latin America responded to a questionnaire on physical and mental health. The CEEISCAT (Centre for Epidemiological Studies of Sexually Transmitted Disease and AIDS in Catalonia), a research group at the IGTP is part of the international consortium Coalition Plus, which carried out LAMIS-18.