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News

- Research

A new cellular model reveals which mutations drive progression to myelodysplastic syndrome and leukemia in patients with GATA2 deficiency

A research team has created the first humanised cellular model to study GATA2 deficiency, a rare genetic disorder that predisposes individuals to severe blood conditions such as myelodysplastic syndrome and leukaemia. The study shows that, although the initial GATA2 mutation weakens haematopoietic stem cells, it is additional mutations -particularly in the SETBP1 gene- that drive disease progression. 

- Projects, Research

Micropores pave the way for infection research

A new study provides a powerful way to study infections in environments that closely mimic human organs. The strategy, tested in a bone-marrow-on-chip model, was developed by researchers from ISGlobal, IGTP, I3S at Porto University, and IN2UB, as part of the HIDDENVIVAX project, funded by "la Caixa" Foundation.

Precision increases in a project led by Germans Trias using AI to detect early facial changes in patients with acromegaly

A project led by the Germans Trias i Pujol University Hospital and Research Institute has developed an AI-based facial recognition system, AcroFace, capable of detecting early signs of acromegaly with 93% accuracy. The researchers are now conducting a larger pilot study with 4,000 images from the general population to confirm these promising results and improve early diagnosis of this rare disease.