At the IGTP TODAY
A study led by researchers from IGTP's Immunology of Diabetes group has identified new microRNA as biomarkers for the partial remission phase, also known as "honeymoon phase", of type 1 diabetes, and has linked the miR-30d-5p microRNA to immunoregulatory processes that may take place during this phase.
The discovery, published in the journal Pathogens, paves the way for accelerating the design of efficient vaccines and treatments against the disease.
A study published in JACC: Clinical electrophysiology evaluates local impedance-based mapping as a tool to identify critical components of ventricular tachycardia after myocardial infarction. It highlights its potential to improve the characterisation of ventricular tachycardia tissues and circuits. The scientists conclude that the technique is feasible and could improve the results of cardiac ablation. The work, which was performed in an animal model, involved researchers from the Heart Failure and Heart Regeneration Research Group (ICREC) at the Germans Trias i Pujol Research Institute (IGTP), the Heart Institute of the Germans Trias Hospital (iCor), the Autonomous University of Barcelona (UAB) and Boston Scientific.
Encouraging news in the framework of the International Day Against Childhood Cancer. The Spanish Association Against Cancer, through its Aid Programmes, has granted 1.2 million euros to the coordinated project "Personalised Medicine for Childhood Liver Cancer". The five-year project will be coordinated by the Germans Trias i Pujol Research Institute (IGTP), under the leadership of Dr Carolina Armengol, with the participation of another four Spanish research groups. All participating groups are members of the CIBER of Hepatic and Digestive Diseases (CIBEREHD).
The Centre for the Development of Industrial Technology (CDTI) and the Carlos III Health Institute (ISCII) will fund the project with 1.8 million euros within the R&D&I call linked to Personalised Medicine and Advanced Therapies in the framework of the Strategic Project for the Recovery and Economic Transformation for Vanguard Health (PERTE for Vanguard Health) in gene therapy for Friedreich's ataxia.
The COVICAT-CONTENT 2023 study begins today, with the aim of monitoring COVID-19 in different cohorts in Catalonia and the rest of Spain. Researchers from the Barcelona Institute for Global Health (ISGlobal) and the GCAT'Genomes for Life project of the Germans Trias i Pujol Research Institute (IGTP) evaluate the genetic and epidemiological determinants associated with the disease, as well as the long-term effects of the pandemic on people's physical and mental health and the evolution of the immune response. In this way, the objective is to help define predictive models and control policies for similar situations in the future.
Researchers from the Clinical Genomics Group at Germans Trias i Pujol Research Institute (IGTP) and the Genetics Service at Germans Trias i Pujol Hospital (HUGTiP) will coordinate the project EURONET-NF, which aims to improve genetic diagnosis for patients with neurofibromatoses and schwannomatosis (NF-SWN). The project, which involves 6 countries, has been awarded around €1.6 million in funding by the European Union for the next 3 years.Researchers from the Clinical Genomics Group at Germans Trias i Pujol Research Institute (IGTP) and the Genetics Service at Germans Trias i Pujol Hospital (HUGTiP) will coordinate the project EURONET-NF, which aims to improve genetic diagnosis for patients with neurofibromatoses and schwannomatosis (NF-SWN). The project, which involves 6 countries, has been awarded around €1.6 million in funding by the European Union for the next 3 years.
Researchers from the GCAT|Genomes for Life project of the IGTP have analysed the genetic basis of 13 pigment traits and their association with diseases. The work has been published this month in Genes.
The Public Health Agency of Catalonia (ASPCAT) has increased the budget granted to the Legionellosis Study Group (GELeg) of the Clinical and Environmental Infectious Diseases Research Group (CEID) of the Germans Trias i Pujol Research Institute (IGTP), ratifying its confidence in the resolution of Legionella outbreaks. The increase is almost double the budget items of previous years and will expand the scope of the work carried out in the laboratory.
The first study, published in Nanomedicine: Nanotechnology, Biology and Medicine, seeks a strategy to safely and definitevely restore self-tolerance in autoimmune diseases; the second, in Archivum Immunologiae et Therapiae Experimentalis, bets on making the most of umbilical cord blood cells, key against hematological diseases
