At the IGTP TODAY

News

- Research

HDAC11 deficiency improves muscle function and regeneration during ageing

Researchers from GRENBA-IGTP have identified the HDAC11 protein, an enzyme involved in cellular regulation, as a new therapeutic target to combat sarcopenia, the loss of muscle mass associated with ageing. The study shows that HDAC11 deficiency reduces muscle atrophy, preserves the muscle stem cell reservoir, promotes regeneration after injury and improves muscle function, opening the door to new strategies to support healthy ageing.

- Research

IGTP-led study identifies an epigenetic signature with prognostic value in metastatic thyroid cancer

Researchers from the Endocrine Tumours group, in collaboration with five university hospitals, have conducted the first comprehensive study of DNA methylation patterns in metastatic differentiated thyroid cancer (DTC). Published in the journal Thyroid, the study identifies an epigenetic signature comprising 156 CpG sites in primary tumours that could help stratify patients according to their risk of developing distant metastases.

- Research

A study led by the CIBEREHD group at Hospital Germans Trias demonstrates for the first time how to reduce the number of colonoscopies and improve the follow-up of patients with Crohn’s disease

Specialists from the Digestive System Department at the Hospital Germans Trias and the Inflammatory Bowel Disease Research Group (GReMII) at IGTP have led and published a unique study that represents an improvement in the monitoring and treatment of patients who have undergone surgery due to one of the main inflammatory bowel diseases: Crohn's disease.