22/03/2024 - Research

A boost to biomedical research with statistical tools: from COVID-19 analysis to data management with REDCapDM

IGTP’s Biostatistics Unit have recently published two notable articles. The first paper, appearing in Scientific Reports, reveals the role of socioeconomic inequalities and vaccination in the spread of the pandemic. The second, published in BMC Medical Research Methodology, introduces REDCapDM, a new R package designed to enhance efficiency and reliability in the management of research data collected through the popular REDCap platform.

21/03/2024 - Conferences, Projects, Research, Success Stories

The international consortium INNOVA4TB wraps up five years of cutting-edge tuberculosis research

On 21 March, the final meeting of INNOVA4TB, a consortium led by IGTP with researchers from around the world, took place. Participants presented the results of the different work packages and evaluated the work done since 2019. IGTP will continue to be involved in other networks such as ADVANCE-TB and SMA-TB.

18/03/2024 - Innovation, Research

Progress in developing specific immunotherapies for type 1 diabetes

Researchers from IGTP and Ahead Therapeutics have been exploring a treatment based on liposome-type nanoparticles to address the autoimmunity of type 1 diabetes for years. A study recently published in the Journal of Autoimmunity examines the response of macrophages to this immunotherapy, serving as a preliminary step before clinical trials.

14/03/2024 - Research

Scientists use an innovative approach to provide relevant insights into a rare neurologic disorder

Researchers from IGTP and BSC-CNS have discovered new genetic mechanisms related to spinocerebellar ataxia type 37. Their research, published in the journal Human Genetics, employed advanced techniques such as CRISPR/Cas9 gene editing, real-time large DNA sequencing and machine learning. The study deepens our understanding of this inherited disease, leading to more precise diagnoses and improved genetic counselling for patients.

13/02/2024 - Research

A newly developed therapeutic strategy offers potential in treating neurofibromatosis type 1 skin tumours

Researchers from IGTP have made progress exploring potential treatments for skin tumours associated with neurofibromatosis type 1. Their findings in cell models have been published in the journal JCI Insight.

12/02/2024 - Outreach, Projects, Research

VIDEO: Life Cycle of 'Plasmodium vivax': Highlighting New Cryptic Erythrocytic Stages

To better understand the complexity of P. vivax infections, the CaixaResearch project "Novel organ-on-a-chip technology to study extracellular vesicles-mediated cryptic infections in Plasmodium vivax malaria" has produced this video to disseminate key insights into cryptic erythrocytic infections. The initiative is led by Hernando A del Portillo and Carmen Fernandez-Becerra, group leaders of the Plasmodium vivax and Exosome Research Group (PvREX) at the Barcelona Institute for Global Health (ISGlobal) and the Germans Trias i Pujol Research Institute (IGTP) in Spain.

06/02/2024 - Research

Alterations in the blood immune system found to increase cancer risk

An international team of researchers identifies the genetic basis and biological processes that influence cancer risk related to alterations in the number of immune cells present in blood. This is a significant advance in the understanding of how the immune system can prevent the appearance of tumours.

02/02/2024 - Projects, Research

COVID-19 vaccination in people with HIV, a pending issue

Two studies by CEEISCAT with the PISCIS cohort show that people living with HIV have been less vaccinated with the full initial regimen against COVID-19

29/01/2024 - Projects, Research, Success Stories

The European Union launches the THRIVE project to improve the prognosis of children and adults with liver cancer

The European Union's project THRIVE held its kick-off meeting on 12 January 2024 in Barcelona. The project is coordinated by Josep M. Llovet (IDIBAPS). IGTP collaborates as a partner through c-LOG, led by Carolina Armengol.

25/01/2024 - Research

New therapeutic strategy for metastatic prostate cancer patients resistant to standard treatment

Researchers from B·ARGO and the Urological Tumour Unit at IGTP and ICO have led a study proposing a new therapeutic strategy based on a combination of kinase inhibitors for metastatic prostate cancer patients who have progressed on standard treatment. The study has been published in the journal Frontiers in Pharmacology.