IGTP in 2025: 12 selected news stories
We look back at the year's most significant news stories, showcasing the dedication and collaboration that define IGTP.
At the IGTP TODAY
News
Germans Trias Hospital launches the first screening program in Catalonia to detect type 1 diabetes before the onset of symptoms
Early diagnosis can help prevent serious complications, reduce hospital admissions and minimise the impact of disease onset in children and adolescents
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A new study explores why the same mutation in the BRAF gene leads to different therapeutic responses to its inhibitors in melanoma and colorectal cancer
Researchers from the B·ARGO at IGTP and ICO have conducted a comparative analysis of the impact of BRAF gene mutations in melanoma and colorectal cancer, published in the journal BBA Reviews on Cancer.
- Research
The antibiotic delafloxacin emerges as a potential therapeutic alternative against Legionella
A study led by IGTP researchers shows that, in a laboratory model, delafloxacin inhibits the intracellular replication of Legionella more effectively than a current standard treatment, supporting its potential therapeutic value and the need for future clinical studies.
- Research
Occupational factors strongly influence Long-COVID risk
Work-related factors play a significant and independent role in the risk of developing Long-COVID, shows a new study based on the COVICAT cohort and led by ISGlobal, in collaboration with the University of Turin and the IGTP. The findings, published in BMJ Occupational & Environmental Medicine, highlight that a substantial share of Long-COVID could be prevented through targeted workplace measures and policies.
- Research
New evidence on the therapeutic potential of extracellular vesicles in kidney injury
Researchers at IGTP have published an article analysing the therapeutic potential of extracellular vesicles derived from mesenchymal stem cells to address kidney injury, reviewing current evidence on how these vesicles can interact with renal tubular epithelial cells.
New study maps the landscape of KRAS mutations and targeted therapies in colorectal cancer
A team of researchers from IGTP and ICO has studied alterations in the KRAS gene in colorectal cancer by combining genomic analyses with a systematic review of targeted compounds and clinical trials. Their findings, published in the journal npj Precision Oncology, provide and updated overview to guide future advances in this cancer's treatment.
- Research
A new cellular model reveals which mutations drive progression to myelodysplastic syndrome and leukemia in patients with GATA2 deficiency
A research team has created the first humanised cellular model to study GATA2 deficiency, a rare genetic disorder that predisposes individuals to severe blood conditions such as myelodysplastic syndrome and leukaemia. The study shows that, although the initial GATA2 mutation weakens haematopoietic stem cells, it is additional mutations -particularly in the SETBP1 gene- that drive disease progression.
Micropores pave the way for infection research
A new study provides a powerful way to study infections in environments that closely mimic human organs. The strategy, tested in a bone-marrow-on-chip model, was developed by researchers from ISGlobal, IGTP, I3S at Porto University, and IN2UB, as part of the HIDDENVIVAX project, funded by "la Caixa" Foundation.
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- Research
Study identifies that the sequence of previous diseases may help predict the risk of long COVID
Provides a new perspective: what matters is not only which previous diseases a person has, but also the order in which they appeared and how they interact. This approach makes it possible to identify risk profiles for long COVID that had not been detected until now. The research was conducted within the framework of the COVICAT study, coordinated in collaboration with ISGlobal.
