At the IGTP TODAY

News

- Success Stories

Bioimplants with extra-cellular vesicles from stem cells can improve cardiac function after an acute myocardial heart attack

Researchers from the ICREC Group (Cardiac Insufficiency and Regeneration) in cardiovascular diseases at the Germans Trias i Pujol Research Institute (IGTP) continue to work on therapeutic technologies to repair cardiac tissue after a heart attack. In an article published in Theranostics, they present a study of extracellular vesicles from mesenchymal stem cells combined with tissue engineering as a therapy to repair the heart after a heart attack. They have carried out the study on a porcine heart attack model at the Centre for Comparative Medicine and Bioimage (CMCiB) at the IGTP.

- Research, Success Stories

Mireia Ramos Rodríguez is awarded the prize for the Best Research Paper by a Predoctoral Student by the Catalan Institute of Health

Mireia Ramos Rodríguez is a bioinformatics post-doctoral researcher; she focusses on defining the changes in cis-regulatory elements that can lead to the development of disease and programming to provide tools for other researchers to carry out their analyses. She has been awarded the Prize for Best Research Paper in Health by a Predoctoral Researcher for her article published in Nature Genetics.

- Research, Success Stories

Virtual lungs to understand the dynamics of tuberculosis lesions within the lungs

The study focusses on understanding the mechanisms that keep the infection latent without the infected person developing the disease. 90% of people infected never develop the active disease, understanding this mechanism so that we can identify them is key to eradicating tuberculosis. The research has been carried out in virtual lungs, developed by computational modelling techniques. These are the first results to be published by the 3Rs Programme at the Centre for Comparative Medicine and Bioimage (CMCiB) which aims to minimize the use of animals in pre-clinical research.

- Research, Success Stories

A study of an atypical form of DM1 will improve the diagnosis and management of this rare disease

The Neuromuscular and Neuropediatric Group at the IGTP, led by Gisela Nogales-Gadea have identified a subset of patients with an atypical type of myotonic dystrophy type 1 (MD1), which develops later and with more severe symptoms than usual. This has important implications for diagnosis of these patients, who can be misdiagnosed or not given the correct prognosis. It is also vital for managing the disease correctly in patients and their families. The study has been published in Human Mutation.