At the IGTP TODAY
The European project aims to evaluate the circulation and impact of emerging SARS-CoV-2 variants of concern through the study of well-characterised cohorts across the world
Researchers at the Germans Trias i Pujol Research Institute (IGTP) discover new facets of the biology of extra-cellular vesicles that will advance their use in therapies. In an article published in the International Journal of Molecular Sciences they describe the importance of glycosylation for the interactions between extracellular vesicles from mesenchymal stem cells and endothelial cells.
The Severe Covid-19 GWAS Group, the group that reported the first genetic analysis in early pandemic (NEJM, 2020), presents now the new results of an extended GWAS meta-analysis of a well-characterized cohort of 3,260 COVID-19 patients with respiratory failure and 12,483 population controls from Italy, Spain, Norway and Germany/Austria, that have been published in Human Molecular Genetics.
An international macro-study in which researchers from the GCAT|Genomes for Life project of the Germans Trias i Pujol Research Institute (IGTP) have participated has located 11 new chromosomal regions involved in susceptibility to SARS-CoV-2 infection and in severity COVID-19 clinic. The work is published in the journal Nature.
Since 2019, around 1,000 immigrants from endemic countries have participated in a new model of diagnosis and management of viral hepatitis that has been designed by the Clinical Virology and New Diagnostic Approaches Research Group of the Germans Trias i Pujol Research Institute (IGTP), in the Microbiology Service of the Germans Trial Hospital (headed by Dr. Elisa Martró), along with the Public and Community Health Team (eSPiC) of Drassanes-Vall d'Hebron International Health Unit.
The COST Programme (European Cooperation in Science and Technology) has approved 70 new actions and Spain is coordinating nine of them, making it second in the ranking of countries leading COST Actions after Italy, which is coordinating ten. Three of the Spanish projects are from the Germans Trias i Pujol Research Institute (IGTP) and two of these are being led by the IGTP. COST Actions run for four years and this round will start in the coming autumn.
The of Fundación Épica of La Fura dels Baus Project, in collaboration with the Institut Germans Trias i Pujol and the Barcelona Institute of Science and Technology will take place from 11-24 July at the old CACI factory in Badalona.
Researchers from the ICREC Group (Cardiac Insufficiency and Regeneration) in cardiovascular diseases at the Germans Trias i Pujol Research Institute (IGTP) continue to work on therapeutic technologies to repair cardiac tissue after a heart attack. In an article published in Theranostics, they present a study of extracellular vesicles from mesenchymal stem cells combined with tissue engineering as a therapy to repair the heart after a heart attack. They have carried out the study on a porcine heart attack model at the Centre for Comparative Medicine and Bioimage (CMCiB) at the IGTP.
The IGTP and the Microbiology Service of the Clinical Laboratory of the North Metropolitan Area led by the researcher Elisa Martró have been the first to carry out the complete sequencing of a sample of monkey pox virus in Spain. This is a milestone in itself, but will also be fundamental for epidemiological surveillance of the infection and the study of future outbreaks as it provides a description of the genetic material of the virus.
The Immunology of Diabetes group have published a study evaluating the effect of prenatal exposure to betamethasone on the risk of developing diabetes type 1 in the Journal of Diabetes Research.
