At the IGTP TODAY

News

- Research

Innovative technique to improve characterisation of ventricular tachycardia substrate

A study published in JACC: Clinical electrophysiology evaluates local impedance-based mapping as a tool to identify critical components of ventricular tachycardia after myocardial infarction. It highlights its potential to improve the characterisation of ventricular tachycardia tissues and circuits. The scientists conclude that the technique is feasible and could improve the results of cardiac ablation. The work, which was performed in an animal model, involved researchers from the Heart Failure and Heart Regeneration Research Group (ICREC) at the Germans Trias i Pujol Research Institute (IGTP), the Heart Institute of the Germans Trias Hospital (iCor), the Autonomous University of Barcelona (UAB) and Boston Scientific.

- Research

A diet rich in plant-based omega-3 is associated with better outcomes in heart failure patients

Higher levels of plant-based omega-3 fats reduce the risk of death and hospital admission in people with heart failure. This is according to a joint study by researchers at Germans Trias i Pujol Hospital and Research Institute and the Hospital del Mar Medical Research Institute, published in the Journal of the American College of Cardiology, involving the follow-up of almost a thousand patients.

- Research

Bioimplants with extra-cellular vesicles from stem cells can improve cardiac function after an acute myocardial heart attack

Researchers from the ICREC Group (Cardiac Insufficiency and Regeneration) in cardiovascular diseases at the Germans Trias i Pujol Research Institute (IGTP) continue to work on therapeutic technologies to repair cardiac tissue after a heart attack. In an article published in Theranostics, they present a study of extracellular vesicles from mesenchymal stem cells combined with tissue engineering as a therapy to repair the heart after a heart attack. They have carried out the study on a porcine heart attack model at the Centre for Comparative Medicine and Bioimage (CMCiB) at the IGTP.

- Research

The ”la Caixa” Foundation provides funding to two innovation projects at the IGTP to accelerate development

The "la Caixa" Foundation aims to bring 20 new biomedical projects with large social  impacts to the market more rapidly within the framework of the CaixaResearch Validate and Consolidate 2021 calls. Two of this year's projects are led by groups from the IGTP. The programme aims to boost innovation and technological and knowledge transfer in the field of biomedicine and health and create new companies based on research

- Research

Researchers identify mutations acquired by blood cells that accelerate heart failure progression

A study published in The Journal of the American College of Cardiology shows that clonal haematopoiesis is an important pathological process that accelerates and aggravates the clinical progression of heart failure, independently of the presence of atherosclerosis. The researchers of the Heart Disease Research Group the IGTP have participated in the study, led by the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and the Hospital Universitario Virgen de Arrixaca in Murcia. 

- Research

Biomaterial scaffolds containing extracellular vesicles from stem cells to control and promote heart muscle repair after heart attack

Scientists of the ICREC group at the Germans Trias i Pujol Research institute (IGTP) continue to refine their technology for repairing cardiac tissue after a heart attack.  In a paper published in Bioactive Materials they present their latest work in which they use implanted scaffolds containing no cells, but extracellular vesicles that promote the repair of myocardium damaged in a heart attack.

- Research

Three IGTP projects selected by the CaixaImpulse Validate Programme

The "la Caixa" Foundation has announced the 23 projects selected for the two arms of the CaixaImpulse Programme in this year's call. 20 are projects in the CaixaImpulse Validate call and three of these are led by the IGTP. These initiatives are focussed on resolving big health challenges such as: resistance to cancer treatment; complications in eye surgery and the use of microwaves to detect stent failures in implanted heart disease patients.

- Campus Can Ruti, Research

A team at Germans Trias treat a patient with a new bio-implant to repair heart tissue after a heart attack

The pioneering surgery that took place last May at the Germans Trias Hospital. The bio-implant, based on umbilical cord stem cells, has been developed by the Cardiovascular Disease Research Group (ICREC) at Germans Trias, led by Antoni Bayés-Genís in a research line, which they have been pursuing for 10 years. The new therapy has been developed with the collaboration of the Blood and Tissue Bank (BST) and the Institute of Bioengineering of Catalonia (IBEC); this is the first step of the application in clinical practice and the group will continue to monitor safety and the capacity of cardiac tissue to recover