At the IGTP TODAY

News

- Research

The ”la Caixa” Foundation provides funding to two innovation projects at the IGTP to accelerate development

The "la Caixa" Foundation aims to bring 20 new biomedical projects with large social  impacts to the market more rapidly within the framework of the CaixaResearch Validate and Consolidate 2021 calls. Two of this year's projects are led by groups from the IGTP. The programme aims to boost innovation and technological and knowledge transfer in the field of biomedicine and health and create new companies based on research

- Research

Researchers identify mutations acquired by blood cells that accelerate heart failure progression

A study published in The Journal of the American College of Cardiology shows that clonal haematopoiesis is an important pathological process that accelerates and aggravates the clinical progression of heart failure, independently of the presence of atherosclerosis. The researchers of the Heart Disease Research Group the IGTP have participated in the study, led by the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and the Hospital Universitario Virgen de Arrixaca in Murcia. 

- Research

Biomaterial scaffolds containing extracellular vesicles from stem cells to control and promote heart muscle repair after heart attack

Scientists of the ICREC group at the Germans Trias i Pujol Research institute (IGTP) continue to refine their technology for repairing cardiac tissue after a heart attack.  In a paper published in Bioactive Materials they present their latest work in which they use implanted scaffolds containing no cells, but extracellular vesicles that promote the repair of myocardium damaged in a heart attack.

- Research

Three IGTP projects selected by the CaixaImpulse Validate Programme

The "la Caixa" Foundation has announced the 23 projects selected for the two arms of the CaixaImpulse Programme in this year's call. 20 are projects in the CaixaImpulse Validate call and three of these are led by the IGTP. These initiatives are focussed on resolving big health challenges such as: resistance to cancer treatment; complications in eye surgery and the use of microwaves to detect stent failures in implanted heart disease patients.

- Campus Can Ruti, Research

A team at Germans Trias treat a patient with a new bio-implant to repair heart tissue after a heart attack

The pioneering surgery that took place last May at the Germans Trias Hospital. The bio-implant, based on umbilical cord stem cells, has been developed by the Cardiovascular Disease Research Group (ICREC) at Germans Trias, led by Antoni Bayés-Genís in a research line, which they have been pursuing for 10 years. The new therapy has been developed with the collaboration of the Blood and Tissue Bank (BST) and the Institute of Bioengineering of Catalonia (IBEC); this is the first step of the application in clinical practice and the group will continue to monitor safety and the capacity of cardiac tissue to recover

- Research

A new tool that makes it possible to adapt treatment for patients with cardiogenic shock has been discovered

Cardiogenic shock is a possible complication of serious heart attack involving an associated mortality rate of approximately 50% of all cases. The combination of this new tool with existing methods renders precise and patient-specific decision-making possible. The research is being led by Dr. Antoni Bayés at Germans Trias and the Proteomics Unit of the CRG and UPF, under Dr. Eduard Sabidó

- Research

A study optimizes the probability of success for allogenic cell therapy in patients with heart failure

Researchers from the Heart Disease Research Group at the IGTP and the CIBER Cardiovascular Group both led by Dr Antoni Bayés prepare the way to optimize reparative cell therapy in heart failure patients. The study, carried out in conjunction with the Immunogenetics and Histocompatibility Laboratory and the Cell Therapy Unit of the Blood and Tissue Bank of Barcelona has studied the HLA allele and the frequency of haplotypes in a cohort of patients with heart failure as the first stage in optimizing future allogenic cell therapies for these patients.

- Research

Non-invasive stent monitoring techniques tested

Researchers have developed a new non-invasive probe to detect the presence of metallic stents and monitor their potential structural failures in models of coronary artery disease. The new probe, which has been successfully tested on a murine model, would enable the substitution of surgical controls in patients with stents with a simple outpatient procedure. The study results from a collaboration between researchers from the Germans Trias i Pujol Research Institute (IGTP), the University of Barcelona (UB) and Universitat Politècnica de Catalunya (UPC).

- Research

A study in patients with heart failure points to new prognostic markers for the disease

Researchers of the Cardiovascular Disease Group and the CIBERCV Group, led by Dr Antoni Bayés Genís, have advanced the study of prognostic markers for heart failure, a progressive disease and a public health problem of the first order. They have studied monocyte (a type of white blood cell) count and distribution in a cohort of 400 outpatients with heart failure with a view to showing their predictive value. The study has been published in PLoS One.