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Two projects from IGTP funded by ”la Caixa” Foundation to transition their innovative research from the laboratory to patients

The first urine test that detects kidney fibrosis as an alternative to kidney biopsies, an initiative from the IVECAT group, and a project applying artificial intelligence to rapidly categorise stroke patients and enhance their recovery chances, from the Neurovascular Research group, are two of the fifteen projects from Catalan research centres selected within the 2023 call of the new CaixaImpulse Healthcare Innovation programme.

- Research

Mesenchymal stem cells reveal mechanisms of action in regulatory B cells independent of interleukin-10 useful for their identification and monitoring

Researchers from the REMAR-IVECAT ("Kidney Related Diseases Research" and "Innovation in VEsicles and Cells for Application in Therapy") group, from the Germans Trias i Pujol Research Institute (IGTP), identify molecular pathways in regulatory B cells that are essential for their therapeutic applications. In the article that has been recently published in Frontiers in Immunology, the use of mesenchymal stem cells has allowed distinguishing the molecules that are essential to monitoring regulatory B cells in kidney transplants. 

- Research

Sugars steer stem cell extracellular vesicles to epithelial cells

Researchers at the Germans Trias i Pujol Research Institute (IGTP) discover new facets of the biology of extra-cellular vesicles that will advance their use in therapies. In an article published in the International Journal of Molecular Sciences they describe the importance of glycosylation for the interactions between extracellular vesicles from mesenchymal stem cells and endothelial cells.