IGTP presents its 2023 Annual Report
The report compiles the institution's key numbers and objectives, as well as its research activities. For the first time, the report also includes a web version that summarises the most relevant aspects.
At the IGTP TODAY
The report compiles the institution's key numbers and objectives, as well as its research activities. For the first time, the report also includes a web version that summarises the most relevant aspects.
Researchers from Barcelona's Germans Trias i Pujol Institute and Josep Carreras Leukaemia Research Institute have found a potential new way to improve the treatment of multiple sclerosis (MS) using a novel combined therapy. The results, published in the Journal of Clinical Investigation, builds on two harmonized Phase I clinical trials funded by the European Union, focusing on the use of Vitamin D3 tolerogenic dendritic cells (VitD3-tolDCs) to regulate the immune response in MS patients. The team is now preparing to move into Phase II trials to further explore these findings.
To keep weight in check, it is not only important to consider what we eat, but also the times at which we eat. According to a study published in the International Journal of Behavioral Nutrition and Physical Activity, there are two specific habits that are associated with a lower body mass index (BMI) in the long term: keeping a longer overnight fast and eating breakfast early. This research was led by ISGlobal and was carried out in collaboration with the GCAT cohort from IGTP.
Several researchers from IGTP took part in this year's European Researchers' Night in Barcelona. They shared their passion for science through talks and led participants of a workshop via a board game into the midst of a tuberculosis epidemic.
Researcher Raquel Guillamat Prats discusses her research on respiratory diseases such as pulmonary fibrosis, respiratory infections, and lung cancer. She also shares her experience of establishing a research group from scratch at IGTP.
Researchers from IGTP have analysed the regulatory B cells of patients who have undergone a kidney transplant, evaluating their potential as predictive markers of organ damage and rejection risk. The study, published in the journal Frontiers in Immunology, highlights the importance of studying the immune system in these cases and proposes new tools for clinical practice.
A new study, published in New England Journal of Medicine, has demonstrated the benefits of placing a clip on the valve instead of the usual medical treatment. The study includes the participation of Professor Antoni Bayés-Genís, principal investigator of the ICREC group and Director of the Heart Institute at Germans Trias Hospital.
IGTP leading the first study in the world to prove that personalised therapies are more effective than classic drugs indicated for the treatment of this rare hormonal disease. It is based on response biomarkers that, depending on what they indicate, allow the best possible treatment to be assigned earlier. In addition to very noticeable facial and skeletal deformities, acromegaly causes severe alterations in other parts of the body. Published in The Journal of Clinical Endocrinology & Metabolism.
This recognition consolidates the position of the IIS-IGTP as a reference centre in the management of biomedical research at the national level and ensures its status as an IIS for the next five years.
A study led by researchers from the Germans Trias i Pujol Research Institute (IGTP) and Institut Català d’Oncologia (ICO) analysed peripheral blood samples from patients with metastatic colorectal cancer and identified a potential biomarker indicating the effectiveness of oxaliplatin-based treatment. The research has been published in the journal Biomedicine & Pharmacotherapy.