Researchers from IGTP have discovered that administering human apotransferrin to mice models affected by intracerebral haemorrhage can mitigate the damaging effects of this severe type of stroke. This finding highlights the promising role of apotransferrin as a pre-hospital and pre-triage frontline treatment for all stroke patients. The study has been published in the journal Antioxidants.
At the IGTP TODAY
Researchers of the Cellular and Molecular Neurobiology (CMN) Research Group at the IGTP have developed and established a novel, reproducible and minimally invasive stroke model in pigs through an endovascular approach. The work has been conducted at the Centre for Comparative Medicine and Bioimage (CMCiB), a centre devoted to translational medicine at the very core of the Can Ruti Campus in Badalona together with the IGTP and the Germans Trias i Pujol University Hospital.
An interactomic study identifies a protein as a possible new therapeutic target to prevent neurodegeneration after stroke
A group of researchers led from the Germans Trias i Pujol Institute have conducted an in-depth in-vitro study into the DAPK1 interactome during stroke conditions. They have identified the proteins in the DAPK1 interactome and singled out LRRFIP1 as a possible therapeutic target for neuroprotection after stroke. The study is published in Antioxidants.
A review paper with first author Marc Melià-Sorolla of the Cellular and Molecular Neurobiology Research Group and published in the International Journal of Molecular Sciences highlights a porcine model as the most suitable for stroke research in the future. The CMCiB-IGTP is equipped to carry out this type of research and the group led by Teresa Gasull are already showing the potential of the non-invasive bioimaging technology.
In February 2019 the Cellular and Molecular Neurobiology Research Group, led by Teresa Gasull at the IGTP published a review paper on various aspects of brain iron chemistry in Frontiers in Neuroscience. A year later the paper is showing excellent impact figures.
The Cellular and Molecular Neurobiology Research Group, led by Teresa Gasull at the IGTP has a mission to carry out basic and translational research into strokes. This week they have published a review of recent advances in the field, which includes the role of the ferroptosis in stroke-induced neurodegeneration and includes references to their own recent publications in the field.