At the IGTP TODAY

News

- Research

Bioimplants with extra-cellular vesicles from stem cells can improve cardiac function after an acute myocardial heart attack

Researchers from the ICREC Group (Cardiac Insufficiency and Regeneration) in cardiovascular diseases at the Germans Trias i Pujol Research Institute (IGTP) continue to work on therapeutic technologies to repair cardiac tissue after a heart attack. In an article published in Theranostics, they present a study of extracellular vesicles from mesenchymal stem cells combined with tissue engineering as a therapy to repair the heart after a heart attack. They have carried out the study on a porcine heart attack model at the Centre for Comparative Medicine and Bioimage (CMCiB) at the IGTP.

- Research

The IGTP and the Clinical Laboratory North Metropolitan Area are the first to publish the complete sequence of a sample of monkey pox virus

The IGTP and the Microbiology Service of the Clinical Laboratory of the North Metropolitan Area led by the researcher Elisa Martró have been the first to carry out the complete sequencing of a sample of monkey pox virus in Spain. This is a milestone in itself, but will also be fundamental for epidemiological surveillance of the infection and the study of future outbreaks as it provides a description of the genetic material of the virus.

- Research

Researchers from Germans Trias and Mateu Orfila Hospital in Menorca identify a new subtype of ataxia

The article describing the new SCA49 subtype has been published in the journal Brain Communications, and is featured as a highlight by its Editorial Board. The new ataxia subtype has been identified by studying members of one family from the island of Menorca. The finding provides a better understanding of the pathological basis of ataxia and opens the door to pre-symptomatic diagnoses and genetic counselling for people with the disorder.

- Research

New biomarkers to monitor and predict the remission phase (honeymoon) in children with type 1 diabetes

A study led by researchers from the Germans Trias i Pujol Research Institute (IGTP) and the Parc Tauli Hospital published in Frontiers in Immunology shows that a sample of peripheral blood can be used to identify levels of cells and molecules of the immune system that are specifically altered during the remission phase in paediatric type 1 diabetes (T1D). These can be used to monitor this phase and predict the progress of the disease.

- Research

The generation of human neurofibromas in mice opens the door to testing new treatments

The Hereditary Cancer Group have published a study in Cell Reports in which they describe the generation of a model system based on induced pluripotent stem cells (iPSCs) that is able to generate human neurofibromas in mice. These tumours arise in people with the genetic disease Neurofibromatosis Type 1, a prevalent condition occurring in one in every 3,000 people. To date, a robust method for generating human neurofibromas in mice has been lacking, and the model developed opens up the possibility of testing new treatments for these tumours.

- Research

The RIGHT PLUS Network presents the results of the LAMIS study on sexual health in gay men and MSN in Latin America

The RIGHT PLUS Network has presented the executive summary of the Latin American MSM (men who have sex with men) Internet Survey (LAMIS-20218), in which 64,655 men who have sex with men in Latin America responded to a questionnaire on physical and mental health. The CEEISCAT (Centre for Epidemiological Studies of Sexually Transmitted Disease and AIDS in Catalonia), a research group at the IGTP is part of the international consortium Coalition Plus, which carried out LAMIS-18.

- Research

Air pollution does not increase the risk of getting infected but does increase the risk of getting sick from COVID-19

Long-term exposure to air pollution is associated with a higher risk of developing COVID-19 among those people who get infected, shows the COVICAT Study led by the Barcelona Institute of Global Health (ISGlobal), a centre supported by the "la Caixa" Foundation, and co-led by the GCAT' Genomes for Life-Germans Trias i Pujol Research Institute (IGTP), Badalona. The study, published in Environment Health Perspectives, provides further evidence on the health benefits of reducing air pollution.

- Research

IV Workshop on translational research on urological tumours. From the laboratory to clinical practice

On 11-12 November the IV Workshop on translational research on urological tumours: from the laboratory to clinical practice took place at the Badalona Conference Centre (BCIN). They were jointly organized by the Germans Trias i Pujol Research Institute (IGTP) and the Badalona Applied Research Group in Oncology (B·ARGO), and the Institut Català d'Oncologia (ICO) and are scientifically accredited by SEOM and SOGUG.

- Research

CEEISCAT researchers coordinate a project identifying the risk factors for severe covid-19 for people living with HIV

A study coordinated by researchers of the Centre for Epidemiological Studies of Sexually Transmitted Disease and AIDS in Catalonia (CEEISCAT) a research group affiliated with and based at the Germans Trias i Pujol Research Institute (IGTP) publish a paper in the HIV Lancet showing the risk factors for suffering severe covid-19 for people living with HIV in Catalonia. The results show that people living with HIV at the same time as other chronic diseases and unsuppressed viral loads have a higher risk of suffering severe covid-19 and should be given priority for testing, medical management and vaccination programmes to protect against SARS-CoV-2.