Job offers

EARLY STAGE RESEARCHER (ESR)

Reference:
2018/15
Deadline:

30/03/2018

INTRODUCTION

The Institute for Health Science Research Germans Trias i Pujol (IGTP) is a public research centre in the Autonomous region of Catalonia in Northern Spain dedicated to increasing scientific knowledge and transferring it to improve the care and lives of patients.

The institute is attached to one of the large teaching hospitals in the Barcelona area; the Germans Trias University Hospital (HUGTP), and is located on the biomedical campus that surrounds it, Campus Can Ruti.  It is a CERCA centre; a member of the biocluster supported and supervised by the Autonomous Catalonian Government.  It is also accredited as a Centre of Excellence by the Instituto Carlos III (Spanish Government) and in this capacity acts as an umbrella organization for scientific research on the campus, where it works closely with the other centres located there.

The Germans Trias Institute carries out research within 8 areas:

  • Science of Behaviour and Substance Abuse
  • Immunology and Inflammation
  • Cardiovascular and Respiratory Diseases
  • Infectious Diseases
  • Endocrine and Diseases of the Metabolism, Bones and Kidneys
  • Diseases of the Liver and Digestive Tract
  • Cancer
  • Neuroscience

Scientists working in these areas publish an average of over 500 papers a year, contribute to improved treatment and healthcare protocols, produce patents and set up spin-off companies in order to improve the lives of patients.

The 2014-2017 Strategic Plan for the IGTP reinforces its traditional role as the cornerstone of research management on the campus but also recognizes the need to further increase synergies between the different research institutes there while also boosting excellence in specific areas.  The IGTP plays a vital role in providing and coordinating transversal services and platforms for all researchers on the campus and promoting quality and innovation.   It fully embraces a solid commitment to society as a whole and recognizes the obligation to continue and increase the amount of training of scientists and healthcare workers and also to carry out activities to inform and involve the public in general in the scientific endeavour.

Cancer Biology and Precision Medicine research group of Dr. Rosell that forms part of the Institute for Health Science research Germans Trias i Pujol (IGTP) is involved in application of translational genetic research to the clinical setting The innovative work of Dr. Rosell's multidisciplinary team has long focused on the design and selection of personalized cancer treatments based on genetic analysis and characterization of each patient's tumor in order to optimize outcomes to treatment.

In our group we have worked since 1998 with circulating-free DNA in non-small cell lung cancer (NSCLC) patients and we continue working on the development of liquid biopsy based tools for cancer screening, diagnosis, prognosis and prediction of treatment response and resistance. For this reason, the implementation of liquid biopsy in the clinical process is our objective, to facilitate the access of this methodology to all our patients.

Liquid biopsies have been heralded as a game changer in cancer management, with blood tests offering a minimally invasive, safe, and sensitive alternative or complimentary approach for tissue biopsies. Blood represents a rich source of information through which solid cancers (and their subtypes) can be detected, identified and classified, and matched to a specific therapy. However, despite the potential of individual approaches, the promise of liquid biopsies has not yet materialized in the clinic. Widespread deployment requires creative next-generation researchers with an innovative mindset with access to a unique toolbox, including medical know-how, molecular diagnostics expertise (from health economics to regulatory), and statistical/bioinformatical proficiency. Currently, there are no comprehensive training programs to address this need. To move the promising liquid biopsy technology out of its infancy, the research program and educational curriculum of the European Liquid Biopsy Academy (ELBA) will cover the entire value chain of diagnostics development and integrate all required disciplines and sectors.

The project itself will specifically focus on comparison and integration of liquid biopsy biosources to develop a diagnostic platform for DETECTION of NSCLC and simultaneous SELECTION of the right treatment.

Overview of the role

We are for an enthusiastic PhD student to join our team at the Institute for Health Science Research Germans Trias I Pujol (IGTP), located in Badalona, Barcelona, Spain. The research position is part of a Marie Skłodowska-Curie Innovative Training Network titled "ELBA: European Liquid Biopsies Academy - Towards widespread clinical application of blood based diagnostic tools". Grant Agreement 765492

Requirements

All suitably qualified candidates irrespective of gender or nationality are welcome to apply as long as the following conditions have been fulfilled:

  • Applicant should be highly motivated and willing to work on the project described
  • Applicants will work in a research project titled "Detection and characterization of circulating cell free tumor DNA (CtDNA) in NSCLC".
  • Applicants should have good knowledge of English, both written and oral
  • Applicants should have a Master in Life Sciences (Biochemistry, Pharmacy, Biology or a related field)
  • Applicants must comply with the mobility rule: At the time of recruitment by the host organization, researchers must not have resided or carried out their main activity (work, studies, etc.) in the country of their host organization for more than 12 months in the 3 years immediately before the starting date. Compulsory national service and/or short stays such as holidays are not taken into account. As far as international organisations are concerned, this rule does not apply to the hosting of eligible researchers. However, the appointed researcher must not have spent more than 12 months at the host organisation in the 3 years immediately prior to their recruitment at the host organization

What we offer

For more information:

Please also visit http://www.germanstrias.org/research/cancer/3/cancer-biology-and-precision-medicine

How to apply:

Applicants should submit a personal statement explaining their motivation (maximal one page), a CV and at least one academic reference as one single PDF file to: rrhh@igtp.cat with copy to  rrosell@iconcologia.net and ichaib(ELIMINAR)@igtp.cat

PLEASE PUT THE REFERENCE in the subject of the mail or your application may not reach the right person.

Deadline for applications:  30 - March- 2018

APPLICATION EVALUATION PROCESS:

All applications will be evaluated by a committee: the Scientific Director, the Project Manager and a member of the steering Committee

Interviews will be carried out until we find suitable candidates to apply to that call (via skype)