G-E 5 Kidney affecting diseases
The Kidney-affecting Diseases Research Group (in Spanish Recerca En Malalties d'Afectació Renal or REMAR) aims to deepen in the knowledge of the aetiopathogenic mechanisms of the diseases that affect kidneys, and to boost the translational research for the benefit of renal patients.
The group is led by Dr Josep Bonet, Chief of the Nephrology Service at the Germans Trias i Pujol Hospital.
Urine exosomes in Transplanted patients
- PI Francesc Borràs, (for more information – see the IVECAT group)
- PI Ricardo Lauzurica, Attending Physician
Renal biopsy is the gold standard procedure to diagnose most of renal pathologies. However, this invasive method is of limited repeatability and often describes an irreversible renal damage .The identification of specific biomarkers in the urinary exosomes can help replacing this technique by a less invasive diagnostic.
Morbid Obesity and renal disease
- PI Maruja Navarro, Attending Physician
- PI Assumpta Serra, Attending Physician
Morbid Obesity plays an important role in promoting chronic kidney disease. Our group has participated in the development of several studies related to MO. We are currently interested in the study and definition of specific genes involved in this pathology.
Proteomics and glomerular disease
Investigating new urinary markers by proteomics is one of the most important challenges in the forthcoming years, as it will allow classifying more specifically and effectively primary renal diseases.
- PI Josep Bonet, Chief of Nephrology Service
Mesenchymal Stem Cells in Kidney Transplant
- PI Marcel·la Franquesa, Postdoctoral Investigator
- PI Francesc Borràs, (more information - See IVECAT group)
The aim of this research is to develop a strategy to optimize the induction of tolerance in clinical transplantation. Based on previous work on the interactions of MSC with other cells, we aim to generate regulatory cells in vitro for therapeutic applications.
- PI Maribel Troya, Attending Physician